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The best way to Use Progesterone

Earlier than contemplating utilizing progesterone, it is vital to grasp that it isn’t a magic bullet, and you will get probably the most profit from implementing a bioenergetic weight-reduction plan strategy that means that you can successfully burn glucose as your major gas, with out stockpiling electrons in your mitochondria and slowing down your power manufacturing. My new ebook, “The Mobile Well being Information: Unlocking the Science of Longevity and Pleasure,” coming quickly, explains this course of intimately.

As soon as you’ve got adjusted your weight-reduction plan, an efficient technique to counteract extra estrogen is to take transmucosal progesterone (utilized to the gums, not orally or transdermally), a pure estrogen antagonist. Progesterone is certainly one of solely 4 hormones that many adults might profit from (the opposite three are thyroid hormone T3, DHEA, and pregnenolone).

Transdermal progesterone shouldn’t be really helpful as a result of excessive ranges of 5-alpha reductase are expressed within the pores and skin, which causes a big proportion of ingested progesterone to be irreversibly transformed, primarily to allopregnanolone, and can’t be transformed again to progesterone.

The best technique to administer progesterone

As I counsel, remember that when progesterone is used via the mucous membrane onto the gums, the FDA believes it’s someway transformed right into a drug and prohibits any firm from saying so on the label, which is why firms like Well being Natura promote their progesterone merchandise as “topical.”

Nevertheless, perceive that it’s utterly authorized for docs to advocate off-label prescriptions for drugs to their sufferers. On this case, progesterone is a pure hormone, not a drug, and could be very protected even in excessive doses. That is totally different from the artificial progesterones known as progestins utilized by pharmaceutical firms, that are often and incorrectly really helpful.

Dr. Ray Pete has performed seminal analysis on progesterone and is arguably the world’s foremost professional on progesterone. He wrote his doctoral dissertation on estrogen in 1982 and has spent most of his profession documenting the necessity for a low-LA weight-reduction plan and transmucosal progesterone supplementation to counteract the risks of extra estrogen.

He decided that the majority solvents didn’t dissolve progesterone properly and located that Vitamin E was the most effective solvent to optimally ship progesterone to the tissues. Vitamin E additionally protects in opposition to harm brought on by LA. One should be very cautious about which Vitamin E one makes use of, as most Vitamin E dietary supplements in the marketplace are nugatory, or moderately, they do extra hurt than good.



It is best to completely keep away from artificial vitamin E (alpha tocopherol acetate – the acetate signifies it is artificial). Pure vitamin E is labeled “d-alpha tocopherol”, which is the pure D-isomer and can be utilized by the physique.

Vitamin E additionally is available in different isomers, and for the D isomer to be efficient, you want the total spectrum of tocopherols and tocotrienols, particularly the beta, gamma and delta sorts. See our Vitamin E label for an instance of a great Vitamin E. Any model with an identical label can be utilized.

Pharmaceutical grade bioidentical progesterone might be bought as Progesterone Powder, Bioidentical Micronized Powder, 10 grams from many on-line shops resembling Amazon for round $40. That is roughly a 12 months’s provide, relying on the dosage you select.

Nevertheless, you will want to purchase a small stainless-steel measuring spoon as you will want 1/64 tsp (25 mg) and 1/32 tsp (50 mg). The same old dose is 25-50 mg, taken half-hour earlier than bedtime, because it has anti-cortisol properties and will increase GABA ranges that will help you sleep higher.

Sadly, this vendor often runs out of inventory. If this occurs to you, attempt Well being Natura’s Merely Progesterone, which is pre-mixed with Vitamin E and MCT oil. Though Well being Natura states that this product is for “topical use solely,” I like to recommend making use of it transmucosally, resembling rubbing it into the gums.

For girls who menstruate, progesterone needs to be taken throughout the luteal part, or second half of the menstrual cycle, which might be decided by beginning the remedy 10 days after the primary day of menstruation and stopping the progesterone as soon as menstruation begins.

For males or ladies who don’t menstruate, progesterone might be taken day by day for 4-6 months after which discontinued for one week. One of the best time to take progesterone is half-hour earlier than bedtime, because it has anticortisol results and will increase GABA ranges that will help you sleep higher.

That is one thing I’ve been doing personally for over a 12 months with superb outcomes. Since I’m a doctor, I’ve no downside with you doing this technique. If you’re not a doctor, please seek the advice of your physician earlier than utilizing this remedy as transmucosal progesterone remedy requires a health care provider’s prescription.

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