The best way to Use Progesterone
Earlier than contemplating the usage of progesterone, you will need to perceive that it isn’t a magic bullet, and biggest profit is achieved by implementing a bioenergetic weight loss program method that enables the physique to successfully burn glucose as its main gas, with out stockpiling electrons within the mitochondria and slowing down power manufacturing. My new ebook, Mobile Well being: A Unified Idea of All Illness for Final Longevity and Pleasure, quickly to be printed, covers this course of intimately.
As soon as you have adjusted your weight loss program, an efficient approach to counteract extra estrogen is to take transmucosal progesterone (utilized to the gums, somewhat than orally or transdermally), a pure estrogen antagonist. Progesterone is certainly one of solely 4 hormones that many adults might profit from (the opposite three are thyroid hormone T3, DHEA, and pregnenolone).
Transdermal progesterone will not be really helpful as a result of excessive ranges of 5-alpha reductase are expressed within the pores and skin, which causes a big proportion of ingested progesterone to be irreversibly transformed, primarily to allopregnanolone, and can’t be transformed again to progesterone.
The best approach to administer progesterone
As I counsel, bear in mind that when progesterone is used by means of the mucous membrane onto the gums, the FDA believes it’s one way or the other transformed right into a drug and prohibits any firm from saying so on the label, which is why firms like Well being Natura promote their progesterone merchandise as “topical.”
Nonetheless, perceive that it’s completely authorized for medical doctors to suggest off-label prescriptions for his or her sufferers. On this case, progesterone is a pure hormone, not a drug, and may be very secure even in excessive doses. That is completely different from the artificial progesterones referred to as progestins utilized by pharmaceutical firms, that are regularly and incorrectly really helpful.
Dr. Ray Peat has completed seminal analysis on progesterone and is arguably the world’s foremost skilled on progesterone. He wrote his doctoral dissertation on estrogen in 1982 and has spent most of his profession documenting the necessity for a low-LA weight loss program and transmucosal progesterone supplementation to counteract the risks of extra estrogen.
He decided that the majority solvents didn’t dissolve progesterone nicely and located that Vitamin E was the perfect solvent to optimally ship progesterone to the tissues. Vitamin E additionally protects towards harm attributable to LA. Very cautious about which Vitamin E you employ, as most Vitamin E dietary supplements in the marketplace are nugatory and can do extra hurt than good.
It is best to completely keep away from artificial vitamin E (alpha tocopherol acetate – acetate signifies it is artificial). Pure vitamin E is labeled “d-alpha tocopherol”, which is the pure D-isomer and might be utilized by the physique.
Vitamin E additionally is available in different isomers, and to be efficient, the D isomer requires a full spectrum of tocopherols and tocotrienols, particularly the beta, gamma and delta varieties. See our Vitamin E label for an instance of an excellent Vitamin E. Any equally labeled model can be utilized.
Pharmaceutical grade bioidentical progesterone might be bought as Progesterone Powder, Bioidentical Micronized Powder, 10 grams from many on-line shops comparable to Amazon for round $40. That is roughly a 12 months’s provide, relying on the dosage you select.
Nonetheless, you have to to purchase a small chrome steel measuring spoon as you have to 1/64 tsp (25 mg) and 1/32 tsp (50 mg). The standard dose is 25-50 mg, taken half-hour earlier than bedtime, because it has anti-cortisol properties and will increase GABA ranges that can assist you sleep higher.
Sadly, this vendor regularly runs out of inventory. If this occurs to you, attempt Well being Natura’s Merely Progesterone, which is pre-mixed with Vitamin E and MCT oil. Though Well being Natura states that this product is for “topical use solely,” I like to recommend making use of it transmucosally, comparable to rubbing it into the gums.
For girls who menstruate, progesterone needs to be taken through the luteal section, or second half of the menstrual cycle, which might be decided by beginning the remedy 10 days after the primary day of menstruation and stopping the progesterone as soon as menstruation begins.
For males or ladies who don’t menstruate, progesterone might be taken each day for 4-6 months after which discontinued for one week. The very best time to take progesterone is half-hour earlier than bedtime, because it has anticortisol results and will increase GABA ranges that can assist you sleep higher.
That is one thing I’ve been doing personally for over a 12 months with superb outcomes. Since I’m a doctor, I’ve no downside with you doing this technique. In case you are not a doctor, please seek the advice of your physician earlier than utilizing this remedy as transmucosal progesterone remedy requires a physician’s prescription.

