DMSO is a naturally occurring substance that has a wide range of distinctive properties which have immense therapeutic potential. In flip, 1000’s of research present DMSO safely1 treats a variety of:
• Injuries such as sprains, concussions, burns, surgical incisions, and spinal cord trauma.
• Strokes, paralysis, many neurological disorders (e.g., Down syndrome and dementia), and numerous circulatory disorders (e.g., Raynaud’s, varicose veins, or hemorrhoids).
• Chronic pain (e.g., from a nasty disc, bursitis, arthritis, or advanced regional ache syndrome).
• Many autoimmune, protein, and contractile disorders comparable to scleroderma, amyloidosis, and interstitial cystitis.
• Head conditions including tinnitus, vision loss, dental problems, and sinusitis.
• Internal organ diseases comparable to pancreatitis, infertility, liver cirrhosis, and endometriosis.
• Many skin conditions together with burns, varicose veins, pimples, hair loss, ulcers, pores and skin most cancers, and plenty of autoimmune dermatologic illnesses.
• Challenging infections comparable to shingles, herpes, power ear or dental infections, and osteomyelitis.
Sadly, as soon as the FDA realized the extent to which DMSO would remodel medication, the company made the choice to erase it from historical past. Because of this, hundreds of thousands of sufferers whom it helped and the 1000’s of research on its therapeutic potential have been largely forgotten. Think about for instance, this 1980 60 Minutes program:
Within the Sixties a miraculous therapy for power ache, traumatic harm, strokes and spinal twine paralysis was found that unfold throughout America like wildfire—till the FDA buried it.
Right here, 60 Minutes uncovered the FDA utilizing the identical playbook they used all through COVID-19. A🧵 pic.twitter.com/Bh0dcjNk5w
— A Midwestern Physician (@MidwesternDoc) October 14, 2024
Fortuitously, as a result of DMSO is efficient for a variety of circumstances, it is caught on like wildfire during the last six months (e.g., I’ve already acquired over 2,000 reports of outstanding responses to DMSO, many for a wide range of “incurable” circumstances).
DMSO and Most cancers
Because of the controversy round DMSO, its pioneers selected to downplay its anticancer potential to keep away from backlash towards “unproven” therapies. Because of this, its cancer-fighting properties stay largely unknown. For instance, earlier on this sequence, I presented hundreds of studies that show DMSO:
• Successfully treats most cancers ache (which is usually very difficult to handle).
• Dramatically reduces most of the problems skilled from radiation remedy and chemotherapy.
• Stops cancers from rising and transforms cancerous cells again into regular cells.
• Considerably will increase the efficiency of anticancer brokers, making it doable to make use of a lot decrease (and thus safer) doses of them whereas concurrently having a better therapy success price.
Among the most outstanding advantages are seen when DMSO is mixed with unhazardous pure most cancers therapies (e.g., lately I reviewed the remarkable results obtained from infusing DMSO mixed with baking soda). Sadly, since there are virtually an infinite variety of mixtures, most haven’t been examined, and plenty of unbelievable ones are doubtless ready to be found.
Observe: DMSO mixtures may also be utilized topically as DMSO transports substances contained in the physique and deep into most cancers cells.
Hematoxylin
Hematoxylin is a powder obtained from the logwood tree, which has been used for hundreds of years as each a dye and a medicinal substance.2 After being adopted by the textile business, its oxidized type (hematein), in 1830, was found to be wonderful for staining many parts of cells together with DNA.3 It has remained one of many major stains utilized in pathology ever since (it is the “H” in H & E stains).
Whereas we at present use a systematized course of to develop medication (based mostly on their molecular targets), prior to now, it was a way more haphazard course of that usually arose from incorrect assumptions.
For instance, the primary antibiotic was developed by mixing a substance recognized to be poisonous to micro organism (arsenic)4 with a dye that stained bacterial cell partitions below the speculation that the dye would enable arsenic to selectively goal micro organism.5
After a long time of failed makes an attempt had been made to copy this strategy, one other “antimicrobial” dye was discovered,6 however earlier than lengthy it was found that the antimicrobial agent was not the dye itself however somewhat a colorless metabolic product of it, sulfanilamide.7
Equally, probably the most outstanding therapies I do know of (Ultraviolet Blood Irradiation) was initially developed below the assumption that exposing your complete circulation to UV mild would sterilize the bloodstream and therefore deal with a deadly an infection.
This didn’t work (it killed the take a look at canines) however earlier than lengthy, the inventor unintentionally solely irradiated a small fraction of the canine’s blood and bought a outstanding outcomes as inputting a small quantity of UV mild into the circulation transforms human physiology and permits the self-healing capability of the physique to deal with a variety of diseases (e.g., UVBI is a highly effective treatment for bacterial and viral infections, circulatory issues and autoimmune illnesses).
Hematoxylin likewise follows the same journey. Eli Jordon Tucker, Jr., M.D. was a extremely adorned orthopedic surgeon in Texas who made many important orthopedic discoveries by means of bone analysis he did in his spare time. This required him to buy cattle bones from a meat packing firm, the place he noticed that many industrial cows had giant cancers overlaying their faces.
Questioning if there was a kind of cancer-resisting antibody in these cows, Tucker started administering extracts of their blood to lab rats and mice with cancers and noticed anticancer exercise for sure varieties of most cancers.
Because it was unclear how a lot of a change was occurring, Tucker regarded for a dye that would stain the tumors, and finally realized that hematoxylin was the proper dye as a result of it stained the cancers one shade and regular cells one other. Sadly, hematoxylin had poor solubility (limiting his capacity to experiment), so as soon as DMSO (a potent solvent) got here into use round 1963, Tucker began utilizing it.
He shortly found it might dissolve a really excessive focus of hematoxylin and that this combination selectively stained cancers leaving regular cells unaffected. Most significantly, there was a “marked improve in central necrosis of the neoplasm,” indicating this combination might doubtlessly get rid of cancers whereas sparing regular cells.8
Tucker then determined to conduct toxicity research (initially in canines) the place he discovered excessive concentrations of IV DMSO blended with hematoxylin (D-hematoxylin) had no toxicity to any of the tissues or organs he examined (and didn’t accumulate in any non-cancerous tissue). Curiously, the combination he made was 4 occasions much less poisonous than IV DMSO alone (which was already extraordinarily secure).
He then started treating spontaneous cancers in animals (e.g., in horses, canines and cows), which included terminal circumstances with huge tumors (e.g., a large-cell lymphosarcoma, a small-cell lymphosarcoma, generalized malignant melanoma, a squamous cell carcinoma) together with an osteogenic sarcoma. In all of those circumstances, there was a immediate response, and the animal subsequently recovered.
Tucker’s Work
Tucker step by step decided a workable dose for D-hematoxylin and earlier than lengthy was approached by a colleague who had a comatose feminine affected person on the verge of dying from inoperable fibrosarcoma. D-hematoxylin brought about her tumor to recede till it may very well be surgically eliminated (at which level she had a full restoration).
Inspired, Tucker handled extra sufferers. Ultimately, in 1968,9 he published results from 37 cancer patients: these receiving D-hematoxylin with different therapies noticed a 70% enchancment price, in comparison with simply 5% on typical therapies alone. Youthful, much less closely handled sufferers did finest, and topical or IV routes proved only.
Tucker’s sufferers included many dramatic recoveries — like a 3-year-old boy with terminal most cancers who lived into his 30s, a girl with aggressive lymphosarcoma cured after a yr of infusions and a high-level Exxon government with superior colon most cancers survived and later accompanied Tucker to the FDA (who regardless of being astonished by Tucker’s circumstances nonetheless stonewalled D-hematoxylin).
Regardless of promising outcomes and minimal negative effects the American Most cancers Society focused the remedy10 and Tucker shortly confronted a heavy backlash and was expelled from his hospital. Justifiably fearing he’d lose his license, he stopped publishing however continued privately treating determined sufferers (typically without cost).
D-hematoxylin light from view, with just a few docs utilizing it quietly over time. However the tales stay: of lives saved, cancers reversed, and a devoted physician who risked all the pieces to supply hope when nobody else would.
Observe: Andrew Ivy (who was arguably probably the most influential physician in America on the finish of World Struggle 2),11 like Tucker theorized there should be an element within the blood which resisted most cancers, and finally got here throughout a isolate (from cows injected with a cancer-causing fungus who’d then recovered) which did simply that.
After refusing to promote out to the AMA (who often tried to purchase out competing therapies), he was blacklisted by each the FDA and AMA, and despite having thousands of compelling and well-documented cases showing it cured cancer, successfully had his total status destroyed as a result of he’d promoted an “unproven most cancers remedy.”
Hematoxylin Persists
After its preliminary discovery, DMSO shortly unfold throughout America, attracting many devoted proponents. As soon as the FDA tried to close down the usage of DMSO, a few of its proponents fought for many years to stop it from being forgotten.
A couple of of these (e.g., comparable to maverick doctor William Campbell Douglass) likewise took up D-hematoxylin, and one medical journalist, podiatrist Morton Walker labored with Tucker in order that his method may very well be preserved in print and proceed to assist sufferers into the long run.12
Considered one of them, Jim McCann (a maverick Canadian engineer and self-taught healer), beginning with a high-dose therapy that saved a person dying of prostate most cancers, started experimenting with D-hematoxylin. He finally needed to relocate to Ecuador, the place he quietly educated round 20 docs. Over time, D-hematoxylin turned a fixture in Ecuador’s various medication scene, utilized by as many as 100 docs.
Years later, an Ecuadorian physician efficiently used DMSO and antibiotics to deal with power bacterial prostatitis, curing 44 of 45 patients. Impressed by McCann, he started utilizing the same strategy for prostate most cancers, mixing hematoxylin with DMSO. The outcomes had been so promising, they sparked a 15-year examine that continues immediately.
Observe: Each Tucker and the Ecuador workforce discovered D-hematoxylin has a really low LD50 (1257.16 mg/kg), which is between 10 to 100 occasions much less poisonous than many generally used most cancers medication.13 Likewise, hematoxylin alone has negligible toxicity.14 As such, apart from fevers or chills (which happen when too excessive of a dose is infused too shortly), no vital negative effects (e.g., indicators of organ injury) have been noticed from D-hematoxylin.
Latest D-Hematoxylin Sufferers
That challenge concerned treating roughly 85 sufferers, with the remedy price in sufferers who had not beforehand acquired chemotherapy averaging between 80% to 90%. As such, D-hematoxylin is a wonderful most cancers therapy, however it isn’t excellent and won’t work for everybody.
The cancers to this point discovered to have a great response to D-hematoxylin (a few of that are in any other case extraordinarily troublesome to deal with) included:
• Leukemias (notably acute leukemias)
• Bile duct most cancers
• Sarcomas (together with gentle tissue sarcomas and osteosarcoma)
• Leiomyosarcoma
• Non-Hodgkin lymphoma
• Ovarian carcinoma
• Mediastinal tumors
• Bladder most cancers
• Cancers with a large cell tumor phenotype
Moreover, if a most cancers marker is related to the tumor (e.g., CEA15 or PSA)16 it’ll typically drop quickly, making it simple to trace the progress of D-hematoxylin.
Observe: There could be an preliminary improve within the tumor marker (because of the most cancers breaking down and releasing its parts to the bloodstream), however this shortly goes down.
As the next circumstances present, most of the enhancements had been fairly profound:
• A 54-year-old lady with Hodgkin’s Lymphoma (72% bone marrow involvement, CD20-positive) totally recovered utilizing solely D-hematoxylin and EDTA. Bone marrow biopsy confirmed most cancers selectively destroyed whereas wholesome cells regrew, with no recurrence after 12 years.
• A 72-year-old leukemia affected person noticed fast anemia enchancment with D-hematoxylin.
Likewise, comparable bone marrow adjustments had been seen in her:
• A 16-year-old male with mediastinal seminoma acquired D-hematoxylin, IV vitamin C, after which chemotherapy (cisplatin + bleomycin with DMSO). He totally recovered.
• A 63-year-old man with cholangiocarcinoma (a uncommon bile duct most cancers) handled with D-hematoxylin, chelation, and vitamin C however no chemotherapy. Tumor markers improved. Moreover, the most cancers particles may very well be seen within the drainage tube (an internal-external percutaneous transhepatic biliary drainage catheter).
Likewise, one other bile duct most cancers affected person had a dramatic enchancment in her tumor markers following D-hematoxylin:
• A 63-year-old man with B-cell lymphoproliferative dysfunction acquired solely 10 days of D-hematoxylin solely and his WBC depend normalized.
• A person who had a secure bladder polyp which turned cancerous following a covid vaccination and when examined had unfold in a big portion of the urinary tract’s endothelium. It was surgically eliminated, however as a result of how far it had unfold, the urologist advised the affected person he would solely survive for 2 months. He then started 5 weeks of intravesical and IV D-hematoxylin and the most cancers by no means returned.
• A 55-year-old feminine who had a mediastinal tumor (sort unknown because it was wrapped 560° across the aorta and therefore couldn’t be biopsied) which totally resolved after 33 day by day D-hematoxylin therapies.
Observe: Her outstanding CT adjustments could be considered here.
• A 27-year-old feminine with acute lymphoblastic leukemia reacted poorly to 2 periods of chemo, was labeled as terminal, after which was began on D-hematoxylin. She had a major enchancment in her most cancers and a simultaneous enchancment in her anemia which continued lengthy after typical therapies for anemia had been halted (which didn’t embrace blood transfusions as she was a Jehovah’s Witness).
Moreover, video footage exhibits previous to her therapy she was very frail and had issue strolling, whereas after 31 days of therapy, she had no issue strolling and regarded vibrant and strong.
Observe: 4 years later, she had a wholesome being pregnant (regardless of native hematologists having erroneously forecasted she would have points together with changing into severely anemic).
Moreover these sufferers confirmed:
• D-hematoxylin was considerably simpler than DMSO alone.
• Some tumors disappear shortly; others change into avascular or fibrotic, halting development and changing into simpler to take away surgically.
• Like many different pure most cancers therapies, the perfect outcomes had been seen in people who had not beforehand acquired chemotherapy. Likewise, each affected person who accomplished their D-hematoxylin protocol and had not beforehand acquired chemotherapy haven’t had any recurrences. Nevertheless, if chemotherapy was given just a few weeks after D-hematoxylin had been began, therapy successes elevated.
• In any other case wholesome people who had the most cancers quickly seem had the perfect response to D-hematoxylin.
How Does D-Hematoxylin Work?
Whereas DMSO has many anticancer properties, they aren’t enough to elucidate the fast adjustments noticed. Nevertheless, just a few clues trace at why this mixture works:
• First, one researcher who studied D-hematoxylin discovered that it selectively travels to tumors however not regular tissue.17
• Second, he discovered that it brought about a dose-dependent alternation of tumor cell morphology and eventual demise that primarily affected the middle of the tumor (which is uncommon as usually chemotherapy impacts the periphery of tumors first, and certain partly as a result of DMSO’s ability to penetrate the cytoplasmic barrier which usually protects tumor cells).
Moreover, these adjustments continued after D-hematoxylin was stopped, suggesting it initiates a degenerative course of in tumors.
Observe: Oral D-hematoxylin, whereas much less potent, additionally displayed these anticancer properties.
• Third, he discovered mobile injury initially started within the nucleus, suggesting D-hematoxylin had an affinity for DNA (which hematein does18). Following this, the most cancers cells, in successive phases, started to interrupt down and digest themselves (autolysis19), after which white blood cells started to invade the tumors to get rid of them.
• Fourth, he discovered that D-hematoxylin appeared to first dissolve the extracellular matrix round most cancers cells first, doubtlessly ravenous them.
Protein Kinase CK2
Protein Kinase CK2,20 when dysregulated, has been implicated in lots of of illnesses,21 together with viral infections comparable to COVID-19, autoimmune illnesses, and neurological circumstances. Of these, it is best recognized for taking part in a key function in most cancers (e.g., its exercise is usually elevated in varied cancers, which contributes to tumor development and poor prognosis).
Hematein in flip, has been proven to inhibit CK2 with a excessive diploma of selectivity22,23,24 through binding to a subunit that’s over expressed in lots of cancers,25,26,27 correlates with a poor prognosis,28,29 and when inhibited, causes most cancers cells to endure programmed cell demise.30,31
A number of research have proven that hematein has selective antitumor results and might set off programmed cell demise in cancers.32,33,34,35 Moreover, like D-hematoxylin, CK2 inhibitors have additionally been proven to extend the sensitivity of cancers to chemotherapy.36,37
Lastly, a lot of the cancers that are extremely inclined to D-hematoxylin are additionally extremely depending on CK2 (notably blood cancers38,39 — which CK2 inhibitors have repeatedly demonstrated efficacy towards40,41,42). Likewise, cells dropping their attachment to the extracellular matrix (which DMSO and hematoxylin had been proven above to dissolve) triggers a type of cell demise (anoikis43), which CK2 confers resistance to in most cancers cells.44
As such, it’s doubtless CK2 performs a pivotal function in D-hematoxylin’s anticancer properties and it’s believable that along with DMSO potentiating hematoxylin, hematoxylin can also be potentiating DMSO’s anticancer properties.
Observe: The opposite potential mechanisms for D-hematoxylin’s anticancer properties we now have recognized are mentioned here.
Conclusion
During the last century, many promising most cancers cures have been found however then forgotten because of the medical business’s hostility in direction of something that threatens the most cancers monopoly. Having regarded by means of many, D-hematoxylin particularly stands out for its excessive diploma of efficacy, which is immensely lucky, as not like a lot of these different forgotten therapies, by advantage of it being composed of two easy and extensively out there chemical substances, it’s nonetheless readily accessible.
As such, I’m immensely grateful to all the individuals who, for the final fifty years, labored tirelessly to protect Dr. Tucker’s discovery and I consider the MAHA motion would be the time when these Forgotten Sides of Medication will ultimately have the ability to emerge.
Creator’s Observe: That is an abridged model of a longer article which matches into extra element on all the information on D-hematoxylin, the prevailing protocols for its use and tips on how to find one of many docs at present offering D-hematoxylin. That article, together with tips for normal DMSO use could be learn here. Moreover, a companion article detailing DMSO’s anticancer properties and the opposite most cancers therapies it enhances could be learn here.
A Observe from Dr. Mercola In regards to the Creator
A Midwestern Physician (AMD) is a board-certified doctor from the Midwest and a longtime reader of Mercola.com. I admire AMD’s distinctive perception on a variety of matters and am grateful to share it. I additionally respect AMD’s want to stay nameless since AMD continues to be on the entrance traces treating sufferers. To seek out extra of AMD’s work, remember to try The Forgotten Side of Medicine on Substack.
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